Non-invasive method to measure glucose in diabetic patients
Colloids and Surfaces B: Biointerfaces, 2024
Abstract
Diabetes mellitus is a common disease that requires frequent monitoring of blood glucose levels. This paper presents a new approach for a non-invasive method for the detection of glucose in patients with diabetes. This is done with the development of paper sensors based on fluorescent nanoparticles with the ability to measure small concentrations of glucose in tear fluid.
This non-invasive method represents a significant advance for glucose detection in patients with diabetes, avoiding invasive detection methods such as painful finger pricks. Using upconversion nanoparticles doped with neodymium and erbium ions, these highly sensitive tools are able to detect glucose with a limit of 22 mg/dL, being effective for the described purpose given that glucose levels in the tear fluid of diabetic patients ranges from 0 to 84 mg/dL.
This approach offers a low-cost, portable, enzyme-free sensor that has the potential to improve the quality of life of diabetic patients.
This non-invasive method represents a significant advance for glucose detection in patients with diabetes, avoiding invasive detection methods such as painful finger pricks. Using upconversion nanoparticles doped with neodymium and erbium ions, these highly sensitive tools are able to detect glucose with a limit of 22 mg/dL, being effective for the described purpose given that glucose levels in the tear fluid of diabetic patients ranges from 0 to 84 mg/dL.
This approach offers a low-cost, portable, enzyme-free sensor that has the potential to improve the quality of life of diabetic patients.
A non-invasive glucose sensor using nanoparticles, enhancing diabetes management through pain-free monitoring and improved patient convenience.
Where does it apply?
El monitoreo no invasivo de la glucosa tiene diversas aplicaciones, principalmente en la gestión de la diabetes, con el que los pacientes pueden monitorear fácilmente sus niveles de glucosa en casa y los proveedores de atención médica pueden evaluarlos con facilidad en entornos clínicos. Además este estudio da lugar a un método basado en una tecnología portátil.
La tecnología también supone un avance más en la investigación de métodos de detección por fluorescencia, gracias al empleo de los conocidos pero poco utilizados cambios en la fluorescencia de las nanopartículas, debido a su interacción con los grupos funcionales OH de la glucosa.
En general, este avance tecnológico tiene el potencial para mejorar los métodos de monitorización de la salud y supone un avance más en la investigación de la fluorescencia de nanopartículas y sus potenciales usos.
La tecnología también supone un avance más en la investigación de métodos de detección por fluorescencia, gracias al empleo de los conocidos pero poco utilizados cambios en la fluorescencia de las nanopartículas, debido a su interacción con los grupos funcionales OH de la glucosa.
En general, este avance tecnológico tiene el potencial para mejorar los métodos de monitorización de la salud y supone un avance más en la investigación de la fluorescencia de nanopartículas y sus potenciales usos.
Why does it matter?
Non-invasive glucose monitoring is vital for both patients and the healthcare industry. It improves the patient experience by reducing the pain of traditional finger or arm pricks, improving quality of life due to the portability of the device and the elimination of the fear associated with the tracking.
Additionally, it is worth noting that economically it has the potential to be a low-cost and easy to store monitoring method due to the use of paper as substrate and the lack of enzyme usage, both for patients and healthcare systems.
Additionally, it is worth noting that economically it has the potential to be a low-cost and easy to store monitoring method due to the use of paper as substrate and the lack of enzyme usage, both for patients and healthcare systems.
Non-invasive method to measure glucose in diabetic patients
Colloids and Surfaces B: Biointerfaces, 2024
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